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Accelerating SNARE-mediated Membrane Fusion by DNA-lipid Tethers
SNARE proteins are the core machinery to drive fusion of a vesicle with its target membrane. Inspired by the tethering proteins that bridge the membranes and thus prepare SNAREs for docking and fusion, we developed a lipid conjugated ssDNA mimic that is capable of regulating SNARE function, in situ....
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888371/ https://ncbi.nlm.nih.gov/pubmed/26439984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506844 |
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