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A programmable DNA origami platform to organize SNAREs for membrane fusion

SNARE complexes are the core molecular machinery of membrane fusion, a fundamental process that drives inter- and intra- cellular communication and trafficking. One of the questions that remain controversial has been whether and how SNAREs cooperate. Here we show the use of self-assembled DNA-nanost...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Xu, Weiming, Nathwani, Bhavik, Lin, Chenxiang, Wang, Jing, Karatekin, Erdem, Pincet, Frederic, Shih, William, Rothman, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950518/
https://ncbi.nlm.nih.gov/pubmed/26938705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b13107
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