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Engineering an osmosensor by pivotal histidine positioning within disordered helices
Histidine kinases (HKs) funnel diverse environmental stimuli into a single autophosphorylation event at a conserved histidine residue. The HK EnvZ is a global sensor of osmolality and cellular acid pH. In previous studies, we discovered that osmosensing in EnvZ was mediated through osmolyte-induced...
Tallennettuna:
| Julkaisussa: | Structure |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6377431/ https://ncbi.nlm.nih.gov/pubmed/30503779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.10.012 |
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