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The inner membrane histidine kinase EnvZ senses osmolality via helix-coil transitions in the cytoplasm

Two-component systems mediate bacterial signal transduction, employing a membrane sensor kinase and a cytoplasmic response regulator (RR). Environmental sensing is typically coupled to gene regulation. Understanding how input stimuli activate kinase autophosphorylation remains obscure. The EnvZ/OmpR...

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Detalhes bibliográficos
Main Authors: Wang, Loo Chien, Morgan, Leslie K, Godakumbura, Pahan, Kenney, Linda J, Anand, Ganesh S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365433/
https://ncbi.nlm.nih.gov/pubmed/22543870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.99
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