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15-deoxy-Δ(12, 14)-prostaglandin J(2) enhances anticancer activities independently of VHL status in renal cell carcinomas

Renal cell carcinoma (RCC) is relatively resistant to chemotherapy and radiotherapy. Clear cell RCC (ccRCC) accounts for the majority of RCC, which have mutations or epigenetic silencing of the von Hippel–Lindau (VHL) gene. VHL-positive Caki-2 cells are killed by an endogenous anticancer substance,...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Koma, Hiromi, Yamamoto, Yasuhiro, Fujita, Tomonari, Yagami, Tatsurou
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377412/
https://ncbi.nlm.nih.gov/pubmed/30815591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.01.001
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