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Enantioselective Synthesis of Indolines, Benzodihydrothiophenes, and Indanes by C–H Insertion of Donor/Donor Carbenes

We employ a single catalyst/oxidant system to enable the asymmetric syntheses of indolines, benzodihydrothiophenes, and indanes by C–H insertion of donor/donor carbenes. This methodology enables the rapid construction of densely substituted five-membered rings that form the core of many drug targets...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Angew Chem Int Ed Engl
Egile Nagusiak: Souza, Lucas W., Squitieri, Richard A., Dimirjian, Christine A., Hodur, Blanka M., Nickerson, Leslie A., Penrod, Corinne N., Cordova, Jesus, Fettinger, James C., Shaw, Jared T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377237/
https://ncbi.nlm.nih.gov/pubmed/30193007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201809344
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