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Long Circulating Genetically Encoded Intrinsically Disordered Zwitterionic Polypeptides for Drug Delivery
The clinical utility of many peptide and protein drugs is limited by their short in-vivo half-life. To address this limitation, we report a new class of polypeptide-based materials that have a long plasma circulation time. The design of these polypeptides is motivated by the hypothesis that incorpor...
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| Published in: | Biomaterials |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6376874/ https://ncbi.nlm.nih.gov/pubmed/30504081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.11.012 |
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