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Safety and Efficacy of Ketamine Versus Ketamine-Fentanyl-Dexmedetomidine Combination for Anesthesia and Analgesia in Rats

Ketamine (KET), a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, is most frequently used as an anesthetic, analgesic, and sedative drug in pediatric clinical practices. However, the adverse effects of KET administration such as psychotic episodes limited the use of KET. The aim of t...

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Bibliographic Details
Published in:Dose Response
Main Authors: Li, Chunzhu, Peng, Jiali, Hu, Rong, Yan, Jia, Sun, Yu, Zhang, Lei, Liu, Wenbin, Jiang, Hong
Format: Artigo
Language:Inglês
Published: SAGE Publications 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376518/
https://ncbi.nlm.nih.gov/pubmed/30792614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1559325819825902
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