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GluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats

Anesthetics are used to produce hypnosis and analgesic effects during surgery, but anesthesia for a long time after the operation is not conducive to the recovery of animals or patients. Therefore, finding appropriate treatments to counter the effects of anesthetics could enhance postoperative recov...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Chunzhu, Yan, Jia, Tang, Dewei, Zhu, Jidong, Huang, Chen, Sun, Yu, Hu, Rong, Wang, Hao, Fu, Chaoying, Chen, Yelin, Jiang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093419/
https://ncbi.nlm.nih.gov/pubmed/32210319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62192-8
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