Enhanced Therapeutic Effect of RGD-Modified Polymeric Micelles Loaded With Low-Dose Methotrexate and Nimesulide on Rheumatoid Arthritis

Angiogenesis plays an essential role in the progression of rheumatoid arthritis (RA). RGD peptide shows high affinity and selectivity for integrin α(v)β(3,) which is one of the most extensively examined target of angiogenesis. Nimesulide could improve the anti-rheumatic profile of methotrexate. But...

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Publicado en:Theranostics
Autores principales: Wang, Yunlong, Liu, Zhongbing, Li, Ting, Chen, Lin, Lyu, Jiayao, Li, Chunhong, Lin, Yan, Hao, Na, Zhou, Meiling, Zhong, Zhirong
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376478/
https://ncbi.nlm.nih.gov/pubmed/30809303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30418
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