Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants

BACKGROUND: Iron is essential for life but contributes to oxidative damage. In Northern-European ancestry populations, HFE gene C282Y mutations are relatively common (0.3%–0.6% rare homozygote prevalence) and associated with excessive iron absorption, fatigue, diabetes, arthritis, and liver disease,...

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Veröffentlicht in:J Gerontol A Biol Sci Med Sci
Hauptverfasser: Tamosauskaite, Jone, Atkins, Janice L, Pilling, Luke C, Kuo, Chia-Ling, Kuchel, George A, Ferrucci, Luigi, Melzer, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
The Journal of Gerontology: Medical Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376086/
https://ncbi.nlm.nih.gov/pubmed/30657865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly270
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