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IRON OVERLOAD AS A TREATABLE CAUSE OF FRAILTY: GENETIC EVIDENCE IN 200,000 SUBJECTS
Iron is essential for life but also causes oxidative damage. The HFE gene C282Y mutation causing excess iron accumulation is the most common genetic disorder in Americans, and is present in 1 in 150 northern Europeans. However, many middle aged adults with this variant appeared to be unaffected. We...
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| Publicado en: | Innov Aging |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6227700/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.226 |
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