Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions

Adenovirus based vectors are of increasing importance for wide ranging therapeutic applications. As vaccines, vectors derived from human adenovirus species D serotypes 26 and 48 (HAdV-D26/48) are demonstrating promising efficacy as protective platforms against infectious diseases. Significant clinic...

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Publicado en:Nat Commun
Main Authors: Baker, Alexander T., Greenshields-Watson, Alexander, Coughlan, Lynda, Davies, James A., Uusi-Kerttula, Hanni, Cole, David K., Rizkallah, Pierre J., Parker, Alan L.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376029/
https://ncbi.nlm.nih.gov/pubmed/30765704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08599-y
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