The co-inhibitory molecule PD-L1 contributes to regulatory T cell-mediated protection in murine crescentic glomerulonephritis

Immune-mediated glomerular diseases like crescentic glomerulonephritis (cGN) are driven by inappropriately regulated cellular and humoral immune responses subsequently leading to renal tissue injury. Recent studies demonstrated the crucial role for regulatory T cells (Tregs) in suppressing pathogeni...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Neumann, Katrin, Ostmann, Annett, Breda, Philippe Christophe, Ochel, Aaron, Tacke, Frank, Paust, Hans-Joachim, Panzer, Ulf, Tiegs, Gisa
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375967/
https://ncbi.nlm.nih.gov/pubmed/30765734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38432-3
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