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The co-inhibitory molecule PD-L1 contributes to regulatory T cell-mediated protection in murine crescentic glomerulonephritis

Immune-mediated glomerular diseases like crescentic glomerulonephritis (cGN) are driven by inappropriately regulated cellular and humoral immune responses subsequently leading to renal tissue injury. Recent studies demonstrated the crucial role for regulatory T cells (Tregs) in suppressing pathogeni...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Neumann, Katrin, Ostmann, Annett, Breda, Philippe Christophe, Ochel, Aaron, Tacke, Frank, Paust, Hans-Joachim, Panzer, Ulf, Tiegs, Gisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375967/
https://ncbi.nlm.nih.gov/pubmed/30765734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38432-3
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