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Mitochondrial Function in Astrocytes is Essential for Normal Emergence from Anesthesia in Mice
BACKGROUND: In mice, restriction of loss of the mitochondrial complex I gene Ndufs4 to glutamatergic neurons confers a profound hypersensitivity to volatile anesthetics similar to that seen with global genetic knockout of Ndufs4. Astrocytes are crucial to glutamatergic synapse functioning during exc...
Tallennettuna:
| Julkaisussa: | Anesthesiology |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375739/ https://ncbi.nlm.nih.gov/pubmed/30707122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000002528 |
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