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Prion-like Mechanisms in Alzheimer Disease
Senile plaques and neurofibrillary tangles are the principal histopathologic hallmarks of Alzheimer disease. The essential constituents of these lesions are structurally abnormal variants of normally generated proteins: Aβ protein in plaques and tau protein in tangles. At the molecular level, both p...
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| Pubblicato in: | Handb Clin Neurol |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375694/ https://ncbi.nlm.nih.gov/pubmed/29887142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-444-63945-5.00016-7 |
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