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Mapping DNA sequence to transcription factor binding energy in vivo

Despite the central importance of transcriptional regulation in biology, it has proven difficult to determine the regulatory mechanisms of individual genes, let alone entire gene networks. It is particularly difficult to decipher the biophysical mechanisms of transcriptional regulation in living cel...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Barnes, Stephanie L., Belliveau, Nathan M., Ireland, William T., Kinney, Justin B., Phillips, Rob
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375646/
https://ncbi.nlm.nih.gov/pubmed/30716072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006226
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