Therapeutic hypercapnia reduces blood–brain barrier damage possibly via protein kinase Cε in rats with lateral fluid percussion injury

BACKGROUND: This study investigated whether therapeutic hypercapnia (TH) ameliorated blood–brain barrier (BBB) damage and improved the neurologic outcome in a rat model of lateral fluid percussion injury (FPI), and explored the possible underlying mechanism. METHODS: Rats underwent lateral FPI and r...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Yang, Wan-Chao, Wang, Qi, Chi, Lai-Ting, Wang, Yue-Zhen, Cao, Hong-Ling, Li, Wen-Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375143/
https://ncbi.nlm.nih.gov/pubmed/30760300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1427-2
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