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Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis

Non-alcoholic fatty liver disease (NAFLD) is linked to obesity and insulin resistance and is the most prevalent chronic liver disease. During the development of obesity and NAFLD, mitochondria adapt to the increased lipid load in hepatocytes by increasing the rate of fatty acid oxidation. In concert...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Khoo, Nicholas K.H., Fazzari, Marco, Chartoumpekis, Dionysios V., Li, Lihua, Guimaraes, Danielle Aparecida, Arteel, Gavin E., Shiva, Sruti, Freeman, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375063/
https://ncbi.nlm.nih.gov/pubmed/30769284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101132
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