Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis

Non-alcoholic fatty liver disease (NAFLD) is linked to obesity and insulin resistance and is the most prevalent chronic liver disease. During the development of obesity and NAFLD, mitochondria adapt to the increased lipid load in hepatocytes by increasing the rate of fatty acid oxidation. In concert...

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Vydáno v:Redox Biol
Hlavní autoři: Khoo, Nicholas K.H., Fazzari, Marco, Chartoumpekis, Dionysios V., Li, Lihua, Guimaraes, Danielle Aparecida, Arteel, Gavin E., Shiva, Sruti, Freeman, Bruce A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375063/
https://ncbi.nlm.nih.gov/pubmed/30769284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101132
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