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Stereoselectivity evaluation of chiral chitosan microspheres delivery system containing rac-KET in vitro and in vivo

The influence of chiral excipient D-chitosan (CS) on the stereoselective release of racemic ketoprofen (rac-KET) microspheres has been investigated in comparison to those microspheres containing individual enantiomers in vitro and in vivo. Stereoselectivity was observed in vitro release test, with R...

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Vydáno v:Drug Deliv
Hlavní autoři: Yin, Li-Na, Zhang, Ya-Wen, Huang, Wen-Hai, Wang, Sheng-Hao, Zheng, Gao-Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374939/
https://ncbi.nlm.nih.gov/pubmed/30744429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1556360
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