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Myeloid Cells Obtained from the Blood but Not from the Tumor Can Suppress T-cell Proliferation in Patients with Melanoma

PURPOSE: Myeloid-derived suppressor cells (MDSC) have emerged as an immune-regulatory cell type that is expanded in tumor-bearing mice, but less is known about their immune-suppressive role in patients with cancer. EXPERIMENTAL DESIGN: To study the importance of MDSC in patients with melanoma, we ch...

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Détails bibliographiques
Publié dans:Clin Cancer Res
Auteurs principaux: Gros, Alena, Turcotte, Simon, Wunderlich, John R., Ahmadzadeh, Mojgan, Dudley, Mark E., Rosenberg, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374773/
https://ncbi.nlm.nih.gov/pubmed/22837179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1108
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