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Phencynonate S-isomer as a eutomer is a novel central anticholinergic drug for anti-motion sickness

To compare and evaluate the differences of stereoselective activity, the binding affinity, metabolism, transport and molecular docking of phencynonate isomers to muscarinic acetylcholine receptor (mAChR) were investigated in this study. The rotation stimulation and locomotor experiments were used to...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Xu, Pingxiang, Liu, Ying, Wang, Liyun, Wu, Yi, Zhou, Xuelin, Xiao, Junhai, Zheng, Jianquan, Xue, Ming
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374516/
https://ncbi.nlm.nih.gov/pubmed/30760797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38305-9
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