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DRUGPATH – a novel bioinformatic approach identifies DNA-damage pathway as a regulator of size maintenance in human ESCs and iPSCs

Genetic and biochemical screening approaches often fail to identify functionally relevant pathway networks because many signaling proteins contribute to multiple gene ontology pathways. We developed a DRUGPATH-approach to predict pathway-interactomes from high-content drug screen data. DRUGPATH is b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Kovacic, Boris, Rosner, Margit, Schlangen, Karin, Kramer, Nina, Hengstschläger, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374489/
https://ncbi.nlm.nih.gov/pubmed/30760778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37491-w
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