Wird geladen...

Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas

Protein disulfide isomerases including PDIA1 are implicated in cancer progression, but underlying mechanisms are unclear. PDIA1 is known to support vascular Nox1 NADPH oxidase expression/activation. Since deregulated reactive oxygen species (ROS) production underlies tumor growth, we proposed that P...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: De Bessa, Tiphany Coralie, Pagano, Alessandra, Moretti, Ana Iochabel Soares, Oliveira, Percillia Victoria Santos, Mendonça, Samir Andrade, Kovacic, Herve, Laurindo, Francisco Rafael Martins
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374413/
https://ncbi.nlm.nih.gov/pubmed/30760703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1402-y
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!