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Phosphorylation negatively regulates exosome mediated secretion of cryAB in glioma cells

Exosomes mediate secretion of crystallin alphaB (cryAB), a well characterized molecular chaperone with anti-apoptotic activity. However, the mechanisms governing its packaging and secretion remained unexplored. In glioma cells, notwithstanding extensive phosphorylation of cryAB at Ser59 followed by...

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Podrobná bibliografie
Vydáno v:Biochim Biophys Acta
Hlavní autoři: Kore, Rajshekhar A., Abraham, Edathara C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374115/
https://ncbi.nlm.nih.gov/pubmed/26620801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.11.027
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