Presence, persistence and effects of pre-treatment HIV-1 drug resistance variants detected using next generation sequencing: A Retrospective longitudinal study from rural coastal Kenya

BACKGROUND: The epidemiology of HIV-1 drug resistance (HIVDR) determined by Sanger capillary sequencing, has been widely studied. However, much less is known about HIVDR detected using next generation sequencing (NGS) methods. We aimed to determine the presence, persistence and effect of pre-treatme...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Hassan, Amin S., Bibby, David F., Mwaringa, Shalton M., Agutu, Clara A., Ndirangu, Kennedy K., Sanders, Eduard J., Cane, Patricia A., Mbisa, Jean L., Berkley, James A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373901/
https://ncbi.nlm.nih.gov/pubmed/30759103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210559
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