Presence, persistence and effects of pre-treatment HIV-1 drug resistance variants detected using next generation sequencing: A Retrospective longitudinal study from rural coastal Kenya

BACKGROUND: The epidemiology of HIV-1 drug resistance (HIVDR) determined by Sanger capillary sequencing, has been widely studied. However, much less is known about HIVDR detected using next generation sequencing (NGS) methods. We aimed to determine the presence, persistence and effect of pre-treatme...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hassan, Amin S., Bibby, David F., Mwaringa, Shalton M., Agutu, Clara A., Ndirangu, Kennedy K., Sanders, Eduard J., Cane, Patricia A., Mbisa, Jean L., Berkley, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373901/
https://ncbi.nlm.nih.gov/pubmed/30759103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210559
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