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PD-L1 expression and its effect on clinical outcomes of EGFR-mutant NSCLC patients treated with EGFR-TKIs

OBJECTIVE: Epidermal growth factor receptor (EGFR) activation was reported to upregulate programmed death-ligand 1 (PD-L1) expression in lung cancer cells and subsequently contribute to immune escape, indicating its critical role in EGFR-driven lung tumors. This study characterized PD-L1 expression...

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Vydáno v:Cancer Biol Med
Hlavní autoři: Bai, Yuchen, Chen, Xiaoxia, Hou, Likun, Qian, Jun, Jiang, Tao, Zhou, Caicun, Ciebiada, Maciej
Médium: Artigo
Jazyk:Inglês
Vydáno: Chinese Anti-Cancer Association 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372913/
https://ncbi.nlm.nih.gov/pubmed/30766753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2018.0223
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