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Bisphosphonates enhance antitumor effect of EGFR-TKIs in patients with advanced EGFR mutant NSCLC and bone metastases

Whether bisphosphonates could enhance the effect of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in non-small-cell lung cancer (NSCLC) patients with EGFR mutation and bone metastases (BM) remains unknown. EGFR mutation status were collected from 1560 patients with NSCLC...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Zhang, Guowei, Cheng, Ruirui, Zhang, Zengli, Jiang, Tao, Ren, Shengxiang, Ma, Zhiyong, Zhao, Sha, Zhou, Caicun, Zhang, Jun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314405/
https://ncbi.nlm.nih.gov/pubmed/28211502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42979
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