X-Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels

Reprogramming female mouse somatic cells into induced pluripotent stem cells (iPSCs) leads to X-chromosome reactivation. The extent to which increased X-chromosome dosage (X-dosage) in female iPSCs compared with male iPSCs leads to differences in the properties of iPSCs is still unclear. We show tha...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Stem Cell Reports
Main Authors: Song, Juan, Janiszewski, Adrian, De Geest, Natalie, Vanheer, Lotte, Talon, Irene, El Bakkali, Mouna, Oh, Taeho, Pasque, Vincent
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372905/
https://ncbi.nlm.nih.gov/pubmed/30639215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.12.004
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares