ACE Insertion/Deletion Polymorphism (rs4646994) Is Associated With the Increased Risk of Multiple Myeloma

Introduction: The insertion (I allele) deletion (D allele) polymorphism of ACE gene (rs4646994) may influence the etiopathogenesis of multiple myeloma (MM). ACE gene is expressed in bone marrow cells and encodes angiotensin converting enzyme (ACE). It converts angiotensin I to active peptide angiote...

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Udgivet i:Front Oncol
Main Authors: Zmorzynski, Szymon, Szudy-Szczyrek, Aneta, Popek-Marciniec, Sylwia, Korszen-Pilecka, Iwona, Wojcierowska-Litwin, Magdalena, Luterek, Małgorzata, Chocholska, Sylwia, Styk, Wojciech, Swiderska-Kołacz, Grazyna, Januszewska, Joanna, Mielnik, Michal, Hus, Marek, Filip, Agata A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372536/
https://ncbi.nlm.nih.gov/pubmed/30788288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00044
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