Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation

Glatiramer acetate (GA) is widely prescribed for the treatment of relapsing-remitting multiple sclerosis, however, the mechanism of action is still not fully understood. We investigated the structural properties of GA and examined alterations to the drug upon injection into the subcutaneous space. F...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Control Release
Egile Nagusiak: Song, Jimmy Y., Larson, Nicholas R., Thati, Sharadvi, Torres-Vazquez, Irma, Martinez-Rivera, Noraida, Subelzu-Aispuru, Natalia J., Leon, Martin A., Rosa-Molinar, Eduardo, Schöneich, Christian, Middaugh, C. Russell, Berkland, Cory J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372117/
https://ncbi.nlm.nih.gov/pubmed/30414463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.11.007
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