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Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity

The epithelial-specific splicing regulators Esrp1 and Esrp2 are required for mammalian development, including establishment of epidermal barrier functions. However, the mechanisms by which Esrp ablation causes defects in epithelial barriers remain undefined. We determined that the ablation of Esrp1...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Lee, SungKyoung, Cieply, Benjamin, Yang, Yueqin, Peart, Natoya, Glaser, Carl, Chan, Patricia, Carstens, Russ P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371790/
https://ncbi.nlm.nih.gov/pubmed/30485810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.097
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