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Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity

The epithelial-specific splicing regulators Esrp1 and Esrp2 are required for mammalian development, including establishment of epidermal barrier functions. However, the mechanisms by which Esrp ablation causes defects in epithelial barriers remain undefined. We determined that the ablation of Esrp1...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lee, SungKyoung, Cieply, Benjamin, Yang, Yueqin, Peart, Natoya, Glaser, Carl, Chan, Patricia, Carstens, Russ P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371790/
https://ncbi.nlm.nih.gov/pubmed/30485810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.097
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