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Refractory and metastatic infantile fibrosarcoma harboring LMNA–NTRK1 fusion shows complete and durable response to crizotinib

Infantile fibrosarcoma (IFS) is a rare soft-tissue sarcoma, which classically presents as an aggressive and rapidly enlarging tumor over the distal extremities of children in their first year of life. The presence of ETV6 and NTRK3 gene rearrangement is characteristic of IFS, which can be detected o...

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Dettagli Bibliografici
Pubblicato in:Cold Spring Harb Mol Case Stud
Autori principali: Bender, Jonathan, Anderson, Bailey, Bloom, David A., Rabah, Raja, McDougall, Rhonda, Vats, Pankaj, Mody, Rajen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371745/
https://ncbi.nlm.nih.gov/pubmed/30709876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a003376
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