Refractory and metastatic infantile fibrosarcoma harboring LMNA–NTRK1 fusion shows complete and durable response to crizotinib

Infantile fibrosarcoma (IFS) is a rare soft-tissue sarcoma, which classically presents as an aggressive and rapidly enlarging tumor over the distal extremities of children in their first year of life. The presence of ETV6 and NTRK3 gene rearrangement is characteristic of IFS, which can be detected o...

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Vydáno v:Cold Spring Harb Mol Case Stud
Hlavní autoři: Bender, Jonathan, Anderson, Bailey, Bloom, David A., Rabah, Raja, McDougall, Rhonda, Vats, Pankaj, Mody, Rajen
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2019
Témata:
Research Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371745/
https://ncbi.nlm.nih.gov/pubmed/30709876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a003376
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