Refractory and metastatic infantile fibrosarcoma harboring LMNA–NTRK1 fusion shows complete and durable response to crizotinib

Infantile fibrosarcoma (IFS) is a rare soft-tissue sarcoma, which classically presents as an aggressive and rapidly enlarging tumor over the distal extremities of children in their first year of life. The presence of ETV6 and NTRK3 gene rearrangement is characteristic of IFS, which can be detected o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cold Spring Harb Mol Case Stud
Prif Awduron: Bender, Jonathan, Anderson, Bailey, Bloom, David A., Rabah, Raja, McDougall, Rhonda, Vats, Pankaj, Mody, Rajen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2019
Pynciau:
Research Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371745/
https://ncbi.nlm.nih.gov/pubmed/30709876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a003376
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