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Increased mitochondrial respiration promotes survival from endoplasmic reticulum stress

Protein misfolding in the endoplasmic reticulum (ER) is accompanied by adaptive cellular responses to promote cell survival. We now show that activation of mitochondrial respiration is a critical component of an adaptive ER stress response, requiring the unfolded protein response (UPR) sensor Ire1,...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Knupp, Jeffrey, Arvan, Peter, Chang, Amy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370866/
https://ncbi.nlm.nih.gov/pubmed/29795335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0133-4
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