Endoplasmic reticulum stress is induced in growth plate hypertrophic chondrocytes in G610C mouse model of osteogenesis imperfecta.

Osteogenesis imperfecta (OI) is a hereditary bone disorder most commonly caused by autosomal dominant mutations in genes encoding type I collagen. In addition to bone fragility, patients suffer from impaired longitudinal bone growth. It has been demonstrated that in OI, an accumulation of mutated ty...

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Udgivet i:Biochem Biophys Res Commun
Main Authors: Scheiber, Amanda L., Guess, Adam J., Kaito, Takashi, Abzug, Joshua M., Enomoto-Iwamoto, Motomi, Leikin, Sergey, Iwamoto, Masahiro, Otsuru, Satoru
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370306/
https://ncbi.nlm.nih.gov/pubmed/30579604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.12.111
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