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Mechanistic framework predicts drug-class specific utility of antiretrovirals for HIV prophylaxis

Currently, there is no effective vaccine to halt HIV transmission. However, pre-exposure prophylaxis (PrEP) with the drug combination Truvada can substantially decrease HIV transmission in individuals at risk. Despite its benefits, Truvada-based PrEP is expensive and needs to be taken once-daily, wh...

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Duwal, Sulav, Dickinson, Laura, Khoo, Saye, von Kleist, Max
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370240/
https://ncbi.nlm.nih.gov/pubmed/30699105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006740
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