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Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes

To achieve the 90-90-90 goals set by UNAIDS, the number of new HIV infections needs to decrease to approximately 500,000 by 2020. One of the ‘five pillars’ to achieve this goal is pre-exposure prophylaxis (PrEP). Truvada (emtricitabine-tenofovir) is currently the only medication approved for PrEP. D...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Duwal, Sulav, Dickinson, Laura, Khoo, Saye, von Kleist, Max
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001963/
https://ncbi.nlm.nih.gov/pubmed/29902179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006155
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