Understanding the Cross-Talk of Redox Metabolism and Fe-S Cluster Biogenesis in Leishmania Through Systems Biology Approach

Leishmania parasites possess an exceptional oxidant and chemical defense mechanism, involving a very unique small molecular weight thiol, trypanothione (T[SH](2)), that helps the parasite to manage its survival inside the host macrophage. The reduced state of T[SH](2) is maintained by NADPH-dependen...

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Udgivet i:Front Cell Infect Microbiol
Main Authors: Kumar, Anurag, Chauhan, Nutan, Singh, Shailza
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Cellular and Infection Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369582/
https://ncbi.nlm.nih.gov/pubmed/30778378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00015
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