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Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria

Energy metabolism has recently gained interest as a target space for antibiotic drug development in mycobacteria. Of particular importance is bedaquiline (Sirturo), which kills mycobacteria by inhibiting the F(1)F(0) ATP synthase. Other components of the electron transport chain such as the NADH deh...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Lee, Bei Shi, Kalia, Nitin P., Jin, Xin Er F., Hasenoehrl, Erik J., Berney, Michael, Pethe, Kevin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369303/
https://ncbi.nlm.nih.gov/pubmed/30530783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005732
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