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Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria
Energy metabolism has recently gained interest as a target space for antibiotic drug development in mycobacteria. Of particular importance is bedaquiline (Sirturo), which kills mycobacteria by inhibiting the F(1)F(0) ATP synthase. Other components of the electron transport chain such as the NADH deh...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6369303/ https://ncbi.nlm.nih.gov/pubmed/30530783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005732 |
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