Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs

Lipid transport is an essential process with manifest importance to human health and disease. Phospholipid flippases (P4-ATPases) transport lipids across the membrane bilayer and are involved in signal transduction, cell division, and vesicular transport. Mutations in flippase genes cause or contrib...

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Gepubliceerd in:J Biol Chem
Hoofdauteurs: Roland, Bartholomew P., Naito, Tomoki, Best, Jordan T., Arnaiz-Yépez, Cayetana, Takatsu, Hiroyuki, Yu, Roger J., Shin, Hye-Won, Graham, Todd R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369285/
https://ncbi.nlm.nih.gov/pubmed/30530492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005876
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