Efficient Prostate Cancer Therapy with Tissue-Specific Homing Peptides Identified by Advanced Phage Display Technology

Selective targeting of drugs to tumor cells is a key goal in oncology. Here, we performed an in vivo phage display to identify peptides that specifically target xenografted prostate cancer cells. This yielded three peptide candidates, LN1 (C-TGTPARQ-C), LN2 (C-KNSMFAT-C), and LN3 (C-TNKHSPK-C); each...

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Vydáno v:Mol Ther Oncolytics
Hlavní autoři: Wada, Akinori, Terashima, Tomoya, Kageyama, Susumu, Yoshida, Tetsuya, Narita, Mitsuhiro, Kawauchi, Akihiro, Kojima, Hideto
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369249/
https://ncbi.nlm.nih.gov/pubmed/30788426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.01.001
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