Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells

G protein-coupled receptor kinase 2 (GRK2) is a ubiquitous member of the GRK family that restrains cellular activation by G protein-coupled receptor (GPCR) phosphorylation leading to receptor desensitization and internalization, but has been identified to regulate a variety of signaling molecules, a...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Palikhe, Sailesh, Ohashi, Wakana, Sakamoto, Takuya, Hattori, Kohshi, Kawakami, Masaaki, Andoh, Tsugunobu, Yamazaki, Hiromi, Hattori, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369205/
https://ncbi.nlm.nih.gov/pubmed/30778300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00059
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