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A de novo shape-motif discovery algorithm reveals preferences of transcription factors for DNA shape beyond sequence-motifs
DNA shape adds specificity to sequence-motifs but has not been explored systematically outside this context. We hypothesized that DNA binding proteins (DBPs) preferentially occupy DNA with specific structures (“shape-motifs”) regardless of whether or not these correspond to high information content...
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| Publicado no: | Cell Syst |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368855/ https://ncbi.nlm.nih.gov/pubmed/30660610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.12.001 |
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