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Electrostatic and Hydrophobic Interactions Mediate Single-Stranded DNA Recognition and Acta2 Repression by Purine-Rich Element Binding Protein B

Myofibroblast differentiation is characterized by increased expression of cytoskeletal smooth muscle α-actin. In human and murine fibroblasts, the gene encoding smooth muscle α-actin (Acta2) is tightly regulated by a network of transcription factors that either activate or repress the 5′ promoter-en...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Rumora, Amy E., Ferris, Lauren A., Wheeler, Tamar R., Kelm, Robert J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368843/
https://ncbi.nlm.nih.gov/pubmed/27064749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00006
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