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Structural Basis of Multisite Single-Stranded DNA Recognition and ACTA2 Repression by Purine-Rich Element Binding Protein B (Purβ)()

A hallmark of dysfunctional fibroblast to myofibroblast differentiation associated with fibrotic disorders is persistent expression of ACTA2, the gene encoding the cyto-contractile protein smooth muscle α-actin. In this study, a PURB-specific gene knockdown approach was used in conjunction with bioc...

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Main Authors: Rumora, Amy E., Wang, Shu-Xia, Ferris, Lauren A., Everse, Stephen J., Kelm, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750979/
https://ncbi.nlm.nih.gov/pubmed/23724822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400283r
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