NRL and CRX define photoreceptor identity and reveal subgroup-specific dependencies in medulloblastoma

Cancer cells often express differentiation programs unrelated to their tissue of origin, although the contribution of these aberrant phenotypes to malignancy is poorly understood. An aggressive subgroup of medulloblastoma, a malignant pediatric brain tumor of the cerebellum, expresses a photorecepto...

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Publicado en:Cancer Cell
Main Authors: Garancher, Alexandra, Lin, Charles Y., Morabito, Morgane, Richer, Wilfrid, Rocques, Nathalie, Larcher, Magalie, Bihannic, Laure, Smith, Kyle, Miquel, Catherine, Leboucher, Sophie, Herath, Nirmitha I., Dupuy, Fanny, Varlet, Pascale, Haberler, Christine, Walczak, Christine, El Tayara, Nadine, Volk, Andreas, Puget, Stéphanie, Doz, François, Delattre, Olivier, Druillennec, Sabine, Ayrault, Olivier, Wechsler-Reya, Robert J., Eychène, Alain, Bourdeaut, Franck, Northcott, Paul A., Pouponnot, Celio
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368680/
https://ncbi.nlm.nih.gov/pubmed/29533784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.02.006
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