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Condensin-dependent chromatin compaction represses transcription globally during quiescence

Quiescence is a stress-resistant state in which cells reversibly exit the cell cycle and suspend most processes. Quiescence is essential for stem cell maintenance and its misregulation is implicated in tumor formation. One of the hallmarks of quiescent cells is highly condensed chromatin. As condens...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Swygert, Sarah G., Kim, Seungsoo, Wu, Xiaoying, Fu, Tianhong, Hsieh, Tsung-Han, Rando, Oliver J., Eisenman, Robert N., Shendure, Jay, McKnight, Jeffrey N., Tsukiyama, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368455/
https://ncbi.nlm.nih.gov/pubmed/30595435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.020
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