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Condensin-dependent chromatin compaction represses transcription globally during quiescence

Quiescence is a stress-resistant state in which cells reversibly exit the cell cycle and suspend most processes. Quiescence is essential for stem cell maintenance and its misregulation is implicated in tumor formation. One of the hallmarks of quiescent cells is highly condensed chromatin. As condens...

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Vydáno v:Mol Cell
Hlavní autoři: Swygert, Sarah G., Kim, Seungsoo, Wu, Xiaoying, Fu, Tianhong, Hsieh, Tsung-Han, Rando, Oliver J., Eisenman, Robert N., Shendure, Jay, McKnight, Jeffrey N., Tsukiyama, Toshio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368455/
https://ncbi.nlm.nih.gov/pubmed/30595435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.020
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